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The complement system distinguishes "self" from "non-self" via a range of specialized cell-surface and soluble proteins. These homologous proteins belong to a family called the "regulators of complement activation (RCA)" or "complement control proteins (CCP)". Complement control proteins work in concert to regulate the system and keep it from damaging host tissue while simultaneously directing it towards foreign particles such as viruses and bacteria, and unwanted material such as cell debris and antibody-antigen complexes. Most of the complement control proteins act on the convertases, C3b.Bb and C4b.2a, which are bimolecular complexes formed early on in the complement cascade. ==Members== The best-studied members of this family are: * Complement receptor 1 (CR1 or CD35) * Membrane cofactor protein (MCP or CD46) * C4b-binding protein (C4BP). * Decay-accelerating factor (DAF or CD55) * Factor H (fH) Other soluble complement regulators that do not belong to the RCA/CCP family are Complement Factor I and C1 inhibitor. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Complement control protein」の詳細全文を読む スポンサード リンク
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